Homeopathy Research - Inflammation
_Inflammation and Homeopathy
Immunological Bystander Reaction of Homeopathy/Homotoxicology
Heine, H.
Institut fuÈ r Antihomotoxische Medizin und
Grundregulationsforschung, Baden-Baden, Germany
Background and Objectives:
Freedmann and Weiner [1] were the first to show that stimulation of T lymphocytes with antigens in a very low dosage (lg quantities/kg body weight) induces anti-inflammatory effects by generating regulatory lymphocytes (Th3 cells). They demonstrated that Th3 cells are capable of synthesizing the anti-inflammatory cytokine-transforming growth factor beta (TGF-b). We tested whether the production of TGF-b may be influenced by low-to middle potentialized
substances traditionally used in homeopathy/homotoxicology.
Methods:
The test system selected comprised whole-blood cultures from 12 healthy donors. 14 different, mainly plant extractions were used at potencies ranging from 1X through 14X. Incubation lasted for 24 hours. The solvent used in preparing the extracts served as control. After the incubation period the concentration of TGF-b was determined by means of a commercially available immunoassay (TGF-b ELISA, HoÈ lzel, Germany). TGF-b production was calculated as percentages of increase in comparison to the control value.
Results:
Compared with the control value, all substances were found positive. The highest amounts of TGF-b where measured with potencies ranging from 2X through 8X (mean value 2.0-fold of control value). A secondary finding was that the preparations showed individual differences with regard to the TGF-b synthesis.
Conclusion: Low- to middle-potentialized homeopathic/antihomotoxic preparations seem to intervene in cell language on the cytokine level. The utilized homeopathic preparations given to whole-blood cultures are capable to stimulate the Th3 cells to synthesize the most anti-inflammatory cytokine TGF-b. This cytokine
down-regulates inflammatory leukocytes and therefore plays an essential role in controlling inflammatory processes. This immunological bystander reaction could serve as a model to explain the good effects of homeopathic/antihomotoxic remedies in the treatment of inflammatory as well as chronic inflammatory processes.
Source : CAMQUEST
Link to Source
Immunological Bystander Reaction of Homeopathy/Homotoxicology
Heine, H.
Institut fuÈ r Antihomotoxische Medizin und
Grundregulationsforschung, Baden-Baden, Germany
Background and Objectives:
Freedmann and Weiner [1] were the first to show that stimulation of T lymphocytes with antigens in a very low dosage (lg quantities/kg body weight) induces anti-inflammatory effects by generating regulatory lymphocytes (Th3 cells). They demonstrated that Th3 cells are capable of synthesizing the anti-inflammatory cytokine-transforming growth factor beta (TGF-b). We tested whether the production of TGF-b may be influenced by low-to middle potentialized
substances traditionally used in homeopathy/homotoxicology.
Methods:
The test system selected comprised whole-blood cultures from 12 healthy donors. 14 different, mainly plant extractions were used at potencies ranging from 1X through 14X. Incubation lasted for 24 hours. The solvent used in preparing the extracts served as control. After the incubation period the concentration of TGF-b was determined by means of a commercially available immunoassay (TGF-b ELISA, HoÈ lzel, Germany). TGF-b production was calculated as percentages of increase in comparison to the control value.
Results:
Compared with the control value, all substances were found positive. The highest amounts of TGF-b where measured with potencies ranging from 2X through 8X (mean value 2.0-fold of control value). A secondary finding was that the preparations showed individual differences with regard to the TGF-b synthesis.
Conclusion: Low- to middle-potentialized homeopathic/antihomotoxic preparations seem to intervene in cell language on the cytokine level. The utilized homeopathic preparations given to whole-blood cultures are capable to stimulate the Th3 cells to synthesize the most anti-inflammatory cytokine TGF-b. This cytokine
down-regulates inflammatory leukocytes and therefore plays an essential role in controlling inflammatory processes. This immunological bystander reaction could serve as a model to explain the good effects of homeopathic/antihomotoxic remedies in the treatment of inflammatory as well as chronic inflammatory processes.
Source : CAMQUEST
Link to Source