My name is Laura Murphy, I am a Biologist and a practitioner of Natural Medicine, I am a qualified Naturopath, Homeopath, Herbalist and Nutritionist. I am passionate about natural medicine and spend innumerable hours researching evidence based natural therapies and disease and rather than hoard all this valuable information on my computer, I decided to set up this humble website. If you have any questions or suggestions please "contact me"
Look to your health; and if you have it, praise God, and value it next to a good conscience; for health is the second blessing that we mortals are capable of; a blessing that money cannot buy - Izaak Walton
Look to your health; and if you have it, praise God, and value it next to a good conscience; for health is the second blessing that we mortals are capable of; a blessing that money cannot buy - Izaak Walton
Crucifying Julian Assange. The media's refusal to defend the WikiLeaks publisher is a betrayal of press freedom - TruthDig
Julian Assange and the Criminalization of Journalism - TruthDig
- Signs of despair rise among Gen X-ers - The increase in despair occurs "regardless of
race, ethnicity, education, and geography."
- Cotinine may play a role in nicotine addiction. Cotinine, a nicotine metabolite, may be amplifying or contributing to the addictive properties of nicotine - NewsWise
- New study finds simple way to inoculate teens against junk food marketing. A simple and brief intervention can provide lasting protection for adolescents against these harmful effects of food marketing. Reframing how students view food-marketing campaigns can spur adolescents, particularly boys, to make healthier daily diet. - NewsWise..
- Could climate change cause infertility? - NewsWise
- New study suggests college students end up in vicious cycle of substance abuse, poor academics and stress - NewsWise
- As weeds outsmart the latest weedkillers, farmers are running out of options - GMWatch
- CEO sees Bayer "massively" affected by herbicide litigation - GMWatch
- Australia set to deregulate "new GM" techniques - GMWatch
- Just 20 Minutes of Contact With Nature Will Lower Stress Hormone Levels, Reveals New Study - Science Daily
- Novel 5-minute workout improves blood pressure, may boost brain function - Science Daily
- One-third of cancer patients use complementary and alternative medicine - Science Daily
Missed some news - Go To Older News
The American Botanical Council report "Breast cancer is the most common cancer in the United States, with 266,120 cases in women and 2,550 cases in men diagnosed in 2018.The majority of women diagnosed with breast cancer will undergo conventional treatment in the form of surgery, radiation, chemotherapy, and/or endocrine therapy. Many of these women seek additional integrative therapies, including botanicals, to improve their tolerance to, and the efficacy of, these conventional treatments.
While the clinical data supporting the use of botanicals concurrent with conventional treatment is far from robust, there is a body of emerging data. One area of interest is the reduction of adverse side effects, which can make conventional treatment a more tolerable experience and improve treatment adherence, thereby supporting better outcomes. This article provides an overview of the current state of evidence for selected botanicals for improving outcomes with conventional therapies.
The American Journal of Clinical Nutrition report "In this cohort of eastern Finnish middle-aged and older men, a higher ratio of animal to plant protein in the diet and higher meat intake were related to increased mortality risk. Furthermore, higher total protein intake appeared to be associated with increased mortality risk mainly among those with a disease history at baseline. Apart from meat intake, other protein sources—that is, dairy, fish, egg, and plant protein sources—were not associated with mortality risk."
The European Journal of Integrative Medicine report "The application of rose oil aromatherapy by inhalation reduced the scores of preoperative anxiety of patients undergoing septorhinoplasty/rhinoplasty."
The Journal Evidence Based Complementary and Alternative Medicine report "This review found that Cordyceps sinensis could benefit patients with GOLD stage 2 to 3 COPD in terms of exercise tolerance and life quality. It may have a potential effect on improving lung function. Cordyceps sinensisseemed to be beneficial in reducing exacerbation and improving symptoms in stable COPD of GOLD stages 2 to 3 with few adverse events. But we could not draw strong conclusions on effectiveness or safety due to methodological weaknesses and risk of bias of the included studies."
The Journal Alternative and Complementary Medicine report "The results indicated that a combination of Melissa officinalis plus Nepeta menthoides was effective for the treatment of insomnia. The severity of insomnia, total PSQI, sleep latency, daytime dysfunction, and sleep disturbance indicators all decreased in the treatment group, and the sleep efficacy, sleep quality, and sleep duration were increased.
The Journal Military Medical Research report "Our findings have honed the existing knowledge base on therapeutic horseback riding (THR), a beneficial intervention for veterans with PTSD, by identifying a clinically meaningful dosage of THR. A 3-week THR program was effective, and a 6-week program produced clinically significant outcomes in PTSD levels. Older veterans, such as the majority in our sample, may have been diagnosed with PTSD decades ago; THR may be particularly promising for them. It may be important for health systems to recognize such promise by supporting THR as a reimbursable complementary therapy."
The British Journal of Nutrition report "This dietary intervention study in healthy volunteers identified specific effects of dark chocolate on digestive and cerebral function. These findings add to the body of literature indicating that naturally occurring substances in chocolate, in particular cocoa flavanols, in isolation and in combination, have measurable biological effects. Future research will establish if these are clinically relevant. Acute and chronic disturbances in bowel function are common in the community and can be a major burden....If the “nutraceutical” effects of dark chocolate or cocoa-based products are confirmed, then this could be a safe and popular alternative to pharmacological treatment. If, as expected, there are also positive effects on well-being, then the combination of peripheral and central effects could be a much needed, novel approach for the treatment of participants with conditions such as irritable bowel syndrome that are affected by both disorders of digestive function and mood
The Journal of Psychoactive Drugs report "Results indicated that psilocybin enhanced divergent thinking and emotional empathy the morning after use. Enhancements in convergent thinking, valence-specific emotional empathy, and well-being persisted seven days after use. Sub-acute changes in empathy correlated with changes in well-being. The study demonstrates that a single administration of psilocybin in a social setting may be associated with sub-acute enhancement of creative thinking, empathy, and subjective well-being. Future research should test whether these effects contribute to the therapeutic effects in clinical populations."
The Journal Nutrition Research report "RNA-Seq Expression Profiling analyses from a pilot clinical trial in which women with breast cancer consumed 2 ounces of walnuts per day for 2 to 3 weeks between the diagnostic biopsy and subsequent surgery showed that gene expression in the tumor was modified in ways expected to slow proliferation, reduce inflammation, reduce metastasis and to increase cancer cell death. It seems likely that if gene expression was modified in the tumor due to consumption of walnuts, then gene expression of any metastatic cells should also be modified thus decreasing risk for cancer recurrence."
The Journal Integrative Medicine report "Complementary and alternative medicine treatment for insomnia has been sought due to the possible adverse effects of conventional pharmacotherapies. We performed a preliminary evaluation of the feasibility of using, and of the effect of a herbal tea (HT002), based on Traditional East Asian Medicine, in mild-to-moderate insomnia.
In conclusion, the preliminary results of the current protocol suggest that 4-week treatment with HT002 may reduce the severity of insomnia symptoms and improve the quality of life."
The Journal Clinical Nutrition report "There is a large body of evidence which supports the role of inflammation in the pathophysiology of mental health disorders, including depression. Dietary patterns have been shown to modulate the inflammatory state, thus highlighting their potential as a therapeutic tool in disorders with an inflammatory basis....These results provide an association between pro-inflammatory diet and risk of depression. Thus, adopting an anti-inflammatory diet may be an effective intervention or preventative means of reducing depression risk and symptoms
The Journal of Child and Adolescent Psychopharmacology report "This study provides evidence for satisfactory outcomes with saffron in treatment of ADHD. In this double-blind randomized trial of C. sativus versus methylphenidate in treatment of ADHD, C. sativus was as effective as methylphenidate. The clinical relevance of these findings was emphasized by improvements seen in both Parent and Teacher Rating Scale scores. Also C. sativus was safe and showed equally or lesser adverse effects.
The Journal Alternative and Complementary Medicine report "This study aimed at identifying areas of consensus among naturopathic experts in IBS. Panelists reached consensus on a 45-item list of reasonable naturopathic approaches for IBS in North America. Consensus was reached in the domains of general approaches to IBS, office visits, tracking progress, testing, interventions, and resources. It is our intention that these results will inform protocol development in future randomized controlled trials. We believe that there is opportunity for future refinement of these consensus guidelines, reflecting an evolving field of evidence-informed practice of naturopathic medicine."
The Journal Complementary and Alternative Medicine report "E-Zhu (Curcuma zedoaria) is known as a classical traditional Chinese medicine and widely used in the treatment of cancers, cardiovascular disease, inflammation, and other diseases. Its main components include curcumol and curcumin, which have anti-inflammatory and antifibrosis effects.
In conclusion, our findings perfectly supported the hypothesis demonstrated that curcumol and curcumin could reduce the expressions of inflammatory factors by inhibiting the NF-κB signaling pathway and TGF-β1/Smads signaling pathway.
The Journal Complementary and Alternative Medicine report " this review included a summary of the data published by many researchers related to the protective and/or treatment role that propolis and/or its active ingredients play against gastrointestinal associated disorders that affect humans. The focus was on the following: oral mucositis, ulcerative colitis, gastrointestinal cancers, and gastric ulcers. Analysis of the published work indicated that the efficacy of propolis in the treatment of gastrointestinal disorders could be attributed to its antioxidants and anti-inflammatory properties.
The Journal Alternative and Complementary and Alternative Medicine report "Despite widespread use, there remains a paucity of research exploring cancer patients’ experiences of receiving complementary therapy treatment. We wanted to gain insight into the experiences of patients using a complementary therapy outpatient service offering aromatherapy, massage, reflexology and Reiki....Qualitative comments collected from this evaluation indicate that complementary therapies can address both physical and emotional concerns often simultaneously and provide a unique therapeutic space for patients. Many patients have not had this experience before and this may introduce them to new methods of addressing complex multi dimensional issues resulting from living with a cancer diagnosis."
The Journal Alternative and Complementary Medicine report "Geriatric depression is a major public health problem in China. The study compared the intervention and follow-up effects of aromatherapy massage and inhalation on symptoms of depression in community-dwelling older adults after an 8-week intervention.
Conclusion: Both aromatherapy massage and aromatherapy inhalation may have important implications for intervening depression in older adults
The Intl Journal. Environ Res. Public Health report "Physical medicine therapies are often used in treating widespread musculoskeletal disorders, such as neck and low back pain. Herbal cataplasms containing rubefacient substances, such as Cayenne pepper, or galenic preparations like Munari cataplasm are commonly used as natural medications to treat painful areas. In this paper we show the effects of a 20-min application of Cayenne pepper and kaolin powder cataplasm (CPC) on healthy subjects. .... The results indicate that the 5% concentration of Cayenne pepper in the preparation of CPC is the best choice, since no additional effects can be obtained with the 10% concentration, and the effects are higher than those observed at the 2.5% concentration. Importantly, 5% CPC application did not induce a significant increase of inflammatory-related biomarkers, suggesting that 20-min application has no negative side effects at systemic levels
The Int. J. Environ. Res. Public Health report "The aim of this study was to examine the relationship between estimated residential exposure to agricultural chemical application and premature mortality from Parkinson’s disease (PD) in Washington State....The relationship between pesticide exposure and premature mortality aligns with previous biological, toxicological, and epidemiological findings. Glyphosate, the world’s most heavily applied herbicide, and an active ingredient in Roundup® and Paraquat, a toxic herbicide, has shown to be associated with the odds of premature mortality from PD.
The University of Illinois at Chicago via NewsWise report "A growing body of evidence supports the idea that alcohol exposure early in life has lasting effects on the brain and increases the risk of psychological problems in adulthood. Now, researchers at the University of Illinois at Chicago have found that adolescent binge drinking, even if discontinued, increases the risk for anxiety later in life due to abnormal epigenetic programming."
The Ramazzini Institute via GMWatch report "Global Glyphosate Study pilot phase shows reproductive and developmental effects at "safe" dose"
A new study has found that exposure to glyphosate-based herbicides (GBHs), including Roundup, caused reproductive and developmental effects in both male and female rats, at a dose level currently considered safe in the US (1.75 mg/kg bw/day). Exposure to GBHs was associated with androgen-like effects, including a statistically significant increase of anogenital distance (AGD) in males and females, delay of first estrus, and increased testosterone in females, in the study conducted by scientists at the Ramazzini Institute, Bologna, Italy.
The Journal Cognitive Behaviour Therapy report "To our knowledge, this is the first meta-analysis to examine the efficacy of Mindfulness Based Cognitive Therapy (MBCT) specifically for patients who are currently experiencing depressive symptoms....Given that MBCT may be of similar efficacy to other active therapies for currently depressed individuals, further research could continue to examine the efficacy of MBCT in other psychiatric conditions (e.g. anxiety disorders).
The European Journal of Integrative Medicine report "Overall, present study suggest that the selected plants such as Cassia occidentalis, Callistemon viminalis, Cleome viscosa and Mimosa hamataexhibited significant cytotoxicity against MCF-7 breast cancer cells along with inhibition of angiogenesis in CAM model and scavenging of free radicals.
The American Academy of Neurology via Newswise report " For people with multiple sclerosis (MS), drinking around 290 calories per day of soda or other sugar-sweetened beverages, or the equivalent of about two cans of non-diet soda, may be tied to more severe symptoms and a higher level of disability compared to people with MS who seldom consume sugar-sweetened beverages, according to a preliminary study."
The Journal Parkinsons Disease report "Aerobic exercise tended to best improve memory in individuals with Parkinsons Disease (PD). Further, exercise in general appears to be associated with improved cognitive function in individuals with PD. However, improvements might be limited to certain cognitive domains (global cognitive function, executive function or memory). Besides cognitive function, exercise, regardless of mode, tended to slow disease progression in individuals with PD
The Journal Molecules report "Obesity is a common but often underrated condition that is globally considered to be a major public health concern that contributes significantly to the rate of morbidity and death. This review has shown the effectiveness of Hibiscus sabdariffa extract (HSE) on obesity-related parameters according to different experimental designs employed in various studies reviewed. Results have consistently reported that HSE consumption reduces body weight, lipid accumulation and total cholesterol metabolism in both animal and human studies. Its effectiveness in inhibiting pancreatic lipase and on adipocyte differentiation has also been frequently reported, thus confirming its therapeutic potential in obesity management. H. sabdariffa extracts are generally considered to have a low degree of toxicity. However, some studies revealed that H. sabdariffa consumption at high doses may have some adverse effects. Hence more animal and clinical studies are required to determine safe doses of H. sabdariffa to balance the therapeutic and toxicological effects
The Iranian Journal of Basic Medical Science report "Chronic neuropathic pain is a common significant and debilitating problem that presents a major challenge to health-care. Despite the large number of available drugs, there are no curative conventional treatments for neuropathic pain. Nowadays, more attention has been focused on the herbal formulation in the field of drug discovery. Therefore, we performed an extensive review about herbal drugs and plants that exhibited protective effects on neuropathic pain... The more common plants which are used for the treatment of neuropathic pain are included as: Acorus calamus, Artemisia dracunculus, Butea monosperma, Citrullus colocynthis, Curcuma longa, Crocus sativus, Elaeagnus angustifolia, Ginkgo biloba, Mitragyna speciosa, Momordica charantia, Nigella sativa, Ocimum sanctum, Phyllanthus amarus, Pterodon pubescens Benth, Rubia cordifolia and Salvia officinalis...
In conclusion, this review suggests that some herbal plants can be suitable candidates for the treatment of neuropathic pain.
The Journal of the American College of Nutrition report "This study evaluated the effect of cinnamon on disease activity, serum levels of some inflammatory markers, and cardiovascular risk factors in women with rheumatoid arthritis (RA)
In conclusion, this study demonstrates the beneficial effect of cinnamon supplement on the improvement of disease activity and inflammatory biomarkers in RA. The findings indicated that the administration of cinnamon at 2000 mg/d for 8 weeks resulted in a significant reduction in serum TNF-a, CRP, tender and swollen joints count, and blood pressure in women with RA. Regarding the availability and lack of side effects, the regular intake of cinnamon supplement may be used as a pharmacological agent in the treatment of RA.
The Journal Chinese Medicine report "Based on our previous investigations on anti-tumor, anti-angiogenic, anti-metastatic, bone protective and immunomodulating activities of various Chinese herbal medicines, four constituent herbs, namely Andrographis paniculata, Acanthopanax senticosus, Camellia sinensis, and Hedyotis diffusa were eventually selected to form an innovative herbal formula.
In summary, our innovative Chinese herbal formula was demonstrated to possess anti-tumor, anti-metastatic and bone-protective activities in metastatic breast tumor-bearing mice. The preclinical data generated in this study would lead to the development of evidence-based supplement as adjuvant therapy for metastatic breast cancer.
The Journal Phytherapy Research report "Of the phytomedicines reviewed, P. methysticum (Kava) has the largest evidence base for use in the anxiety disorders, with tripartite level of support from in vitro, in vivo, and human clinical studies. Thus, P. methysticum remains the hallmark anxiolytic phytomedicine (minor concerns over liver toxicity notwithstanding). It is the most strongly evidenced for generalised anxiety, with clinical investigations now examining GABA metabolite changes via neuroimaging, and whether individual gene differences in GABA pathway polymorphisms influence treatment response. V. officinalis, C. asiatica, M. recutita, G. biloba, P. incarnata, and W. somnifera offer the next most extensive evidence for reducing anxiety through GABA‐related pathways; all with preclinical studies of GABA‐ergic action in rodent animal models, with human studies
The Journal Food and Function report "The present meta-analysis showed that consumption of apples and pears was significantly associated with decreased risk of Type 2 Diabetes Mellitus (T2DM). Furthermore, dose–response analysis indicated that apple and pear consumption was inversely associated with T2DM risk in a dose-dependent trend
The Journal Nature report "Sleep is integral to life. Although insufficient or disrupted sleep increases the risk of multiple pathological conditions, including cardiovascular disease2, we know little about the cellular and molecular mechanisms by which sleep maintains cardiovascular health. Here we report that sleep regulates haematopoiesis and protects against atherosclerosis in mice."
The Journal Neurology, Neurosurgery & psychiatry report "Our findings suggest that MS patients with allergies have more active disease than those without allergies, and that this effect is driven by food allergies. We showed that patients with food allergy have a 1.3 times significantly higher rate for cumulative number of attacks compared with patients with no allergies, along with a 2.5 times higher likelihood of having a Gad-enhancing lesion on brain MRI. The environmental allergy and drug allergy groups did not show major differences when compared with the group with no reported allergies"
The Journal Pain report "The present study shows that mindful individuals are less sensitive to pain and exhibit significantly lower activation in the precuneus/dPCC, central nodes of self-referential and nociceptive processing.... These findings could be utilized to better develop adjunctive pain therapies (biofeedback; mindfulness meditation; dialectical behavioral therapy) to specifically target increases in trait mindfulness and reductions in PCC/precuneus activity to treat pain.
The Journal Nutrients report "Evidence from published reports is reasonably strong to indicate that consumption of cherries decreased markers for oxidative stress, inflammation, exercise-induced muscle soreness and loss of strength, and blood pressure acutely after ingesting cherries. Limited numbers of published reports also indicate beneficial effects of consuming cherries on arthritis, diabetes, blood lipids, sleep, cognitive functions, and possibly mood. It should be noted that many of these studies, which suggested health benefits of cherry consumption, used amounts (45–270 cherries/day) that might be considered to be a high dose."
The Journal Evidence Based Complementary and Alternative Medicine report " Sleep plays an important role in individuals’ health. The functions of the brain, the cardiovascular system, the immune system, and the metabolic system are closely associated with sleep. As a prevalent sleep disorder, insomnia has been closely concerned, and it is necessary to find effective therapies. In recent years, a growing body of studies has shown that mind-body therapies (MBTs) can improve sleep quality and ameliorate insomnia severity.....MBTs can be effective in treating insomnia and improving sleep quality for healthy individuals and clinical patients.
Restorative Neurology and Neuroscience report "Yoga, a mind body intervention re-established immunological tolerance by aiding remission at molecular and cellular level along with significant reduction in depression. Thus in this inflammatory arthritis with a major psychosomatic component, yoga can be used as a complementary/adjunct therapy."
Avicenna Journal of Phytomedicine report ":Aging is a multifactorial phenomenon, which attribute to different diseases and abnormalities in living systems. Oxidative stress, which is an important factor in aging, exacerbates this process via different mechanisms. Crocin (CR), one of the active components of saffron showed strong antioxidant effects. In the present study, anti-aging property of crocin was investigated in mice....Administration of crocin reduced d-galactose-induced aging in mice through inhibition of oxidative stress, reduction of inflammation and elevation of sex hormones"
Avicenna Journal of Phytomedicine report "Saffron has beneficial effects on depression and homocysteine level in patients with major depression."
The Journal Cannabis and Cannabinoid Research report "Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide, and new therapeutic strategies are still required. Here we screened a synthetic cannabinoid library to identify compounds that uniformly reduce the viability of seven CRC cell lines......We identified three families of cannabinoid compounds that reduce CRC cell viability through a noncanonical receptor mechanism. Future modification of these compounds may lead to the development of novel therapies to treat this disease."
The Journal Environmental Research report "An organic diet was associated with significant reductions in urinary excretion of several pesticide metabolites and parent compounds. This study adds to a growing body of literature indicating that an organic diet may reduce exposure to a range of pesticides in children and adults. Additional research is needed to evaluate dietary exposure to neonicotinoids, which are now the most widely used class of insecticides in the world."
The American Journal of Physiology—Renal Physiology report "Zinc deficiency (ZnD) is implicated in hypertension, in part, by promoting cardiovascular and renal 224 dysfunction. However, a direct link had not been established. In this study, we directly explored the role of Zn2+ 225 bioavailability in Blood Pressure (BP) regulation. Using both in vivo and in vitro models of ZnD, our novel findings indicated that 1) Zn2+ contributes to BP regulation via modulating renal Na+ 226 transport, 2) renal NCC mediates ZnD-induced hypertension and 3) NCC is a Zn2+ 227 -regulated transporter that is 228 upregulated by ZnD"
Environmental Health News report "Kids exposed to phthalates prenatally and as 3-year-olds have decreased motor skills later in their childhood, according to a new study.The study is concerning because phthalates are so widely used. Previous research found that phthalate exposure is linked to decreased motor skills for infants and toddlers but this is the first study to suggest these problems may persist as the children age.
"As lower scores on measures of motor development have been associated with more problems in cognitive, socioemotional functioning and behavior, the findings of this study have implications related to overall child development," the researchers wrote in the study published online in Environmental Research.
The Journal of Nutrition report "This meta-analysis provides evidence that breakfast skipping is associated with an increased risk of type 2 diabetes, and the association is partly mediated by BMI."
The Journal Nutrients report "To sum up, the present study provides initial clinical evidence about the independent and deleterious effect of both low adherence to the MedDiet and low physical activity practice on lung function in subjects without known pulmonary disease. More prospective and clinical trial interventions are warranted in the future to confirm the effectiveness of a healthy diet and physical activity in preventing respiratory disorders."
The Journal Chinese Medicine report "Baduanjin, a traditional Chinese exercise therapy, has been widely used in China to treat type 2 diabetes (T2DM) with depression (DD). However, the underlying mechanism of Baduanjin in anti-DD is unclear. This study was focused on investigating the effects of Baduanjin on symptoms of depression and blood glucose in patients with DD and the underlying mechanism....it was confirmed that Baduanjin is a safe and effective intervention for patients with DD because it can effectively ameliorate the symptoms of depression and blood glucose levels in patients with DD by regulating the dysregulated expression of lncRNA, mRNA, and circRNA.
The Journal Evidence Based Complementary and Alternative Medicine report "Cervicitis is a common sexually transmitted disease. In recent years, the abuse of antibiotic in the treatment of cervicitis results in the emergence of antibiotic-resistant bacteria; alternative strategies are needed to be developed. In this research, we investigated the effects of Feilin Vaginal Gel (FVG), a Chinese herbal formula, on the treatment of cervicitis. ... These results suggest that FVG is capable of treating cervicitis through the inhibition of pathogens and the regulation of host immune responses. FVG may contribute as an alternative agent for the treatment of cervicitis."
The Journal Alternative and Complementary Medicine report "Administration of oral Cannabidiol (CBD) in addition to routine psychiatric care was associated with post-traumatic stress disorder (PTSD) symptom reduction in adults with PTSD. CBD also appeared to offer relief in a subset of patients who reported frequent nightmares as a symptom of their PTSD
The Journal lanta Medica report "Licorice has been traditionally recognized as a “guide drug” (drugs that enhance the effectiveness and reduce the toxicity of other ingredients) and is added to most traditional and modern prescriptions. Basic in vitro and in vivo pharmacological studies indicate that the combined treatment of licorice compounds, such as GA, ISLG, and LCA, with clinical chemotherapy drugs presents both synergistic antineoplastic effects and a reduction of the side effects of chemotherapeutics GL also reverses cisplatin resistance in hepatocellular carcinoma cells. Furthermore, GL pretreatment enhances UVB-induced apoptosis in melanoma cells, blocks UVB-induced skin tumor formation, and hinders ionizing radiation-induced tumor cell extravasation and lung metastasis. All of these findings indicate that a combined therapy may provide an optimal venue for licorice compounds in clinical application."
The Journal Complementary Therapies in Medicine report "In summary, this review provides some evidence that propolis can be a good alternative to the topical application of acyclovir in cases of HSV-1 infections"
JAMA Psychiatry report "Using genetic instruments identified from large-scale GWAS, robust evidence supports a protective relationship between objectively assessed—but not self-reported—physical activity and the risk for Major Depressive Disorder (MDD). Findings point to the importance of objective measurement of physical activity in epidemiologic studies of mental health and support the hypothesis that enhancing physical activity may be an effective prevention strategy for depression.
The Journal Evidence Based Complementary and Alternative Medicine report "Airway mucus hypersecretion is the main pathogenic factor in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and the control of mucus secretion is closely associated with survival. Louqin Zhisou decoction (LQZS) has been found to improve lung function and reduce sputum in AECOPD patients, but the mechanism remains unclear. In summary, this study demonstrated that LQZS could inhibit mucus hypersecretion in airway of AECOPD.
The Avicenna Journal of Phytomedicine report "In conclusion, our study showed that hydro alcoholic extract of UD prevents establishment of atherosclerotic lesions in rat aorta, which is associated with positive effects on serum lipid profile without significantly affecting antioxidant status."
The Environmental Sciences Europe report "EPA and IARC reached diametrically opposed conclusions on glyphosate genotoxicity for three primary reasons: (1) in the core tables compiled by EPA and IARC, the EPA relied mostly on registrant-commissioned, unpublished regulatory studies, 99% of which were negative, while IARC relied mostly on peer-reviewed studies of which 70% were positive (83 of 118); (2) EPA’s evaluation was largely based on data from studies on technical glyphosate, whereas IARC’s review placed heavy weight on the results of formulated GBH and AMPA assays; (3) EPA’s evaluation was focused on typical, general population dietary exposures assuming legal, food-crop uses, and did not take into account, nor address generally higher occupational exposures and risks. IARC’s assessment encompassed data from typical dietary, occupational, and elevated exposure scenarios. More research is needed on real-world exposures to the chemicals within formulated GBHs and the biological fate and consequences of such exposures."
The Journal JNCI Cancer Spectrum report "Acupressure was associated with greater improvements than usual care in anxiety, pain, and symptoms of depression in breast cancer survivors with troublesome fatigue. These findings warrant further evaluation in suitably controlled randomized trials."
Antimicrobial and Antileishmanial Activity + Cinnamomum zeylanicum, Origanum vulgare, and Curcuma longa Essential Oils
The Journal Evidence Based Complementary and Alternative Medicine report "The major compounds in the essential oils were cinnamic aldehyde (C. zeylanicum), turmerone (C. longa), and cis-p-Menth-2-en-1-ol (O. vulgare). All three essential oils exhibited antimicrobial action, highlighting C. longaessential oil against S. aureus. Antileishmanial activity against promastigote forms of L. amazonensis was observed to C. longa essential oil, but not to C. zeylanicum and O. vulgare essential oil. C. longa essential oil activity against intracellular amastigote is the first description of activity against the parasite form found in mammal host, ensuring their potential antileishmanial activity. C. longa essential oil did not induce NO production in BALB/c peritoneal macrophages, suggesting that intracellular amastigote activity may be related to other mechanisms."
The Journal of Alternative and Complementary Medicine report "All herbal preparations used in human studies have led to the alleviation of symptoms related to GERD. Myrtus communis and Cydonia oblonga showed marked reduction in GERD symptoms comparable to omeprazole. The therapeutic effect of Cydonia oblonga persisted after discontinuation of the drug. Tongjlang and rikkunshito showed therapeutic effects for non-erosive reflux disease (NERD) where PPIs failed to show a promising effect. Studies on Ceratonia siliqua have been solely focused on regurgitation in infants, and a remarkable decrease in the number of regurgitations was demonstrated.Conclusion: The multiple mechanisms of action of medicinal plants in GERD other than anti-secretory properties appear to provide more efficient treatment and helped to manage the histopathological changes associated with this disorder. Further studies are needed to understand the effects of medicinal plants on GERD better.
The Journal Cannabis and Cannabinoid Research report "The current available data on the pharmacology of cannabis root components provide significant support to the historical and ethnobotanical claims of clinical efficacy. Certainly, this suggests the need for reexamination of whole root preparations on inflammatory and malignant conditions employing modern scientific techniques."
The Journal Alternative and Complementary Medicine report "Keeping in view the current guidelines for treatment of diarrhea, honey is considered one of the potential candidates for treatment of diarrhea because it contains a natural combination of probiotics, prebiotics, and zinc. "
The Japanese Journal of Clinical Oncology report "We conclude that there is convincing evidence that cigarette smoking increases the risk of cervical cancer among Japanese women.
The Journal Chinese Medicine report "Our findings suggest that moxibustion treats IBS by modulating the gut microbiota. We demonstrate that moxibustion could potentially be used to regulate gut microbiota imbalances and therefore to treat patients with IBS."
The Journal Nutrients report "plant-based, multi-vitamin/mineral, and phytonutrient (PMP) supplementation for eight weeks reduced reactive oxygen species (ROS) and prevented DNA damage without altering endogenous antioxidant system, and several plasma vitamins and phytonutrients were significantly correlated with ROS scavenging and prevention of DNA damage. Gene expression analysis in PBMC after PMP supplementation showed subtle changes in superoxide metabolic processes."
The Journal Planta Medica report "In summary, our results clearly suggest that saffron reduces the severity of depression based on HAM‑D and BDI scores, but the optimum dose and duration of treatment is still unclear. In the analyzed studies, the frequency of adverse reactions did not differ significantly from that of the placebo groups."
The Journal Evidence Based Complementary and Alternative Medicine report "In conclusion, Camellia sinensis extracts in a dose of 0.6% significantly promote more collagen and fibronectin deposition with higher expression of NO, promoting angiogenesis process via molecular controlling of circulating hypoxia responsive microRNAs: miR-424, miR-210, miR-199a, and miR-21 in diabetic and nondiabetic wounds. Our results support a functional role of circulating hypoxia responsive microRNAs, miR-424, miR-210, miR-199a, and miR-21, as a potential therapeutic targets in angiogenesis and vascular remodeling in diabetic wound healing."
The Journal Evidence Based Integrative Medicine report "Cellulite remains an obstinate clinical and cosmetic problem. In this study, we adapted the Thai traditional noninvasive treatment formulated with 5 additional herbals to improve blood flow, edema, and lipolysis, thereby augmenting cellulite treatment. This was a double-blind, randomized placebo-controlled paired trial....No adverse actions were reported, and there were no dropouts, no missing data, and 100% adherence. Herbal compresses were efficacious against cellulite and thigh sizes. The herbal formula might be adapted to other delivery options, and rationally added herbals may increase effectiveness of traditional therapies and more sustainable actions."
The Journal of Nutrition report "In conclusion, our study adds to the growing body of knowledge supporting the benefits of hazelnut consumption. A large fraction of the US population has inadequate intakes of many minerals and vitamins, including vitamin E (2–4, 22)—especially older adults, who often have lower intakes of micronutrients from food sources. Vitamin E is a so-called “shortfall” micronutrient [identified in the Dietary Guidelines for Americans as a micronutrient which is frequently consumed at levels below the EAR (vitamin E: 12 mg/d)]. Therefore, promoting good dietary sources of vitamin E is important. Despite the limitations of this study, the significant increase in the α-tocopherol metabolite α-CEHC indicates that hazelnut consumption can improve vitamin E status and supports the notion of increased hazelnut consumption as part of a healthy dietary pattern."
The Journal Evidence Based Integrative Medicine report "The use of Psyllium seed in the treatment of functional constipation in patients with GERD is very safe, effective, cheap, and easily available, and this treatment also minimizes the chance of recurrence of GERD compared to omeprazole."
The Middle East Fertility Society Journal report "Many of the studied plants including Soybean, Raspberry, A. vera, L. pumila, C. nucifera, G. max, and G. glabra have anti-androgenic property and certain plants such as: P dactylifera, G. max, C. sinensis, M. piperita and T. vulgaris have antioxidant property that are effective in treating PCOS through improving the serum levels of sex hormones and decreasing oxidative stress. In the light of the evidence, different types of phytoestrogens and antioxidant compounds found in medicinal plants can improve PCOS symptoms and therefore be effectively used to treat this syndrome."
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