Research - Rosa rugosa
The Serum Lipid Lowering Effect of Rugosa Rose Petal Extract Rich in Polyphenols in Adults with High Serum Triglyceride
Takashi YAMAGISHI1,2, Keiji TAKANO1,3, Sumio KONDO41
Harunire Bio Institute Ltd.2 Kitami Institute of Technology3 DRC Ltd.4 Medical Corporation Kenshou-kai Fukushima Health Care Center
Objective: Hypertriglyceridemia or elevated serum triglyceride (TG) is a leading risk factor for developing atherosclerotic cardio-vascular diseases. This clinical study was designed to test the potential of polyphenol-rich extract from Rosa rugosa petals (PE) for improving hypertriglyceridemia and other types of dyslipidemia.
Methods: An open-label clinical study was conducted on 19 male and female adult subjects with elevated serum TG (120–399mg/dL), who were intervened the study diet containing (in a daily dose) 200mg of PE once daily for sss4 weeks. The serum levels of TG and cholesterols were measured at baseline and week-4. The efficacy was evaluated by comparing the measurements at these two time points.
Results: A significant decrease (P<0.05) in serum TG, as well as in serum total cholesterol and non HDL-cholesterol, and a marginal-ly significant decrease (P=0.070) in serum LDL-cholesterol were observed, while serum HDL-cholesterol was virtually not changed. The study diet was well tolerated without any untoward side effect
.Conclusions: The PE-containing diet appears to have benefits in improving hypertriglyceridemia and hypercholesterolemia
Source : Japanese Journal of Complementary and Alternative Medicine
Link to Abstract